Anti-ALDH1A1 Antibody [SY11-02]
ET1605-24
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetALDH1A1
Overview
- SupplierHUABIO
- Product NameAnti-ALDH1A1 Antibody [SY11-02]
- Delivery Days Customer7
- ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- Applications SupplierWB,IHC-P,IP
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDSY11-02
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID216
- Target nameALDH1A1
- Target descriptionaldehyde dehydrogenase 1 family member A1
- Target synonymsALDC, ALDH-E1, ALDH1, ALDH11, HEL-9, HEL-S-53e, HEL12, PUMB1, RALDH1, aldehyde dehydrogenase 1A1, 3-deoxyglucosone dehydrogenase, ALDH class 1, ALHDII, RALDH 1, acetaldehyde dehydrogenase 1, aldehyde dehydrogenase 1, soluble, aldehyde dehydrogenase, liver cytosolic, epididymis luminal protein 12, epididymis luminal protein 9, epididymis secretory sperm binding protein Li 53e, retinal dehydrogenase 1, retinaldehyde dehydrogenase 1
- HostRabbit
- IsotypeIgG
- Protein IDP00352
- Protein NameAldehyde dehydrogenase 1A1
- Scientific DescriptionAldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during the detoxification of alcohol-derived acetaldehyde; metabolism of corticosteroids, biogenic amines and neurotransmitters; and lipid peroxidation. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1), aldehyde dehydrogenase family 1 member A1, aldehyde dehydrogenase cytosolic, ALDHII, ALDH-E1 or ALDH E1, is a retinal dehydrogenase that participates in the biosynthesis of retinoic acid (RA). There are two major liver isoforms of ALDH1 that can localize to cytosolic or mitochondrial space. The ALDH1A2 (RALDH2, RALDH2-T) gene produces three different transcripts and also catalyzes the synthesis of RA from retinaldehyde. ALDH1A3 (ALDH6, RALDH3, ALDH1A6) is a 37 kb gene that consists of 13 exons and produces a major transcript of approximately 3.5 kb most abundant in salivary gland, stomach and kidney. ALDH3A1 (stomach type, ALDH3, ALDHIII) forms a cytoplasmic homodimer that preferentially oxidizes aromatic aldehyde substrates. ALDH genes upregulate as a part of the oxidative stress response, and appear to be abundant in certain tumors that have an accelerated metabolism toward chemotherapy agents.
- ReactivityHuman, Mouse
- Reactivity SupplierHuman,Mouse
- Reactivity Supplier NoteRat
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161