Anti-ALDH4A1 Antibody [7E2]

HUABIO

Anti-ALDH4A1 Antibody [7E2]

7

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P

Research Use Only

Monoclonal

7E2

2 mg/ml

Unconjugated

ALDH4A1

aldehyde dehydrogenase 4 family member A1

ALDH4, P5CD, P5CDh, delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, L-glutamate gamma-semialdehyde dehydrogenase, P5C dehydrogenase, aldehyde dehydrogenase family 4 member A1, epididymis secretory sperm binding protein, mitochondrial delta-1-pyrroline 5-carboxylate dehydrogenase

Mouse

IgG1

Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde, lipid peroxidation and metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH4A1 (aldehyde dehydrogenase 4 family member A1), also known as P5CD (Delta-1-pyrroline-5-carboxylate dehydrogenase), P5CDh, P5CDhL, P5CDhS or ALDH4, is a major enzyme involved in the proline degradation pathway. Localizing to the mitochondrial matrix, ALDH4A1 catalyzes the conversion of Delta-1-pyrroline-5-carboxylate (P5C) to glutamate. A mutation in the gene encoding ALDH4A1 results in HPII (hyperprolinemia type II), a disease characterized by an excess of P5C and proline that is associated with mental retardation and seizures.

Human, Rat

Human,Rat

-20°C,2°C to 8°C

41116161