Anti-ALDH5A1/SSADH Mouse mAb

PTM BIO

Anti-ALDH5A1/SSADH Mouse mAb

5

Western Blot, ImmunoHistoChemistry Paraffin

WB, IHC-P

Research Use Only

Monoclonal

13331

Unconjugated

Mouse

IgG

Succinate-semialdehyde dehydrogenase, mitochondrial

Succinate-semialdehyde dehydrogenase is an enzyme that in humans is encoded by the ALDH5A1 gene. This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD+-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter gamma-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.

Stable for 12 months from date of receipt/reconstitution.

Human

Human

Protein G purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203