Anti-Alpha 1 Acid Glycoprotein Antibody

HUABIO

Anti-Alpha 1 Acid Glycoprotein Antibody

7

Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P,FC

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

ORM1

orosomucoid 1

A1AG1, AGP-A, AGP1, HEL-S-153w, ORM, alpha-1-acid glycoprotein 1, AGP 1, OMD 1, epididymis secretory sperm binding protein Li 153w

Rabbit

IgG

Alpha-1-acid glycoprotein 1

AGP (alpha1-acid glycoprotein) is an acute phase plasma protein synthesized by the liver. It functions to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, it also mediates the extravasation of cells during infection and inflammation. Expression of AGP is induced by acute-phase stimulatory agents such as bacterial lipopolysaccharides. AGP has a high affinity, low capacity binding for basic drugs at physiological pH. In human plasma, AGP is found at levels of 0.5-1.4 mg/ml, though this is elevated during acute inflammation, and, as a result, levels of this protein can be used to diagnose inflammatory conditions. AGP-1 and AGP-2 contain five and six potential N-glycosylation sites, respectively. Abnormal expression of the APG-1 gene is linked to sarcoidosis and other immunogenetic diseases, while mutations in the APG-2 gene are associated with different types of carcinomas.

Human, Mouse, Rat

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161