Anti-Alpha-2-macroglobulin Antibody [B1-D7]
M1510-24
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetA2M
Overview
- SupplierHUABIO
- Product NameAnti-Alpha-2-macroglobulin Antibody [B1-D7]
- Delivery Days Customer7
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- Applications SupplierWB,IHC-P,ELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDB1-D7
- Concentration2 mg/ml
- ConjugateUnconjugated
- Gene ID2
- Target nameA2M
- Target descriptionalpha-2-macroglobulin
- Target synonymsA2MD, CPAMD5, FWP007, S863-7, alpha-2-macroglobulin, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5, alpha-2-M
- HostMouse
- IsotypeIgG1
- Protein IDP01023
- Protein NameAlpha-2-macroglobulin
- Scientific DescriptionIs able to inhibit all four classes of proteinases by a unique trapping mechanism. This protein has a peptide stretch, called the bait region which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region, a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
- ReactivityHuman
- Reactivity SupplierHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161