Anti-alpha+beta Synuclein Antibody [ST05-21]

HUABIO

Anti-alpha+beta Synuclein Antibody [ST05-21]

7

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,IHC-P,FC

Research Use Only

Monoclonal

ST05-21

1 mg/ml

Unconjugated

SNCB

synuclein beta

beta-synuclein, I(2)-synuclein

Rabbit

IgG

Alpha-synuclein

The synucleins, including alpha-synuclein (also designated NACP for nonamyloid component precursor), beta-synuclein (also designated PNP 14 for phospho-neuroprotein 14) and gamma-synuclein (also designated persyn or BCSG1 for breast cancer-specific gene 1) are presynaptic proteins abundant in neurons. Synucleins are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. alpha-Synuclein, identified as a component of Alzheimers disease amyloid plaques, is localized to neuronal cell bodies and synapses. Coordinate expression of alpha-synuclein and beta-synuclein may be important during hematopoetic cell differentiation. A mutant form of alpha-synuclein is found in patients with early onset Parkinsons disease. gamma-Synuclein is associated with axonal pathology in Parkinsons disease.

Human, Mouse, Rat

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161