Anti-Alpha-crystallin [B4m3]
Ab03593-1.1
ApplicationsELISA, Other Application
Product group Antibodies
ReactivityBacteria
TargethspX
Overview
- SupplierAbsolute Antibody
- Product NameAnti-Alpha-crystallin [B4m3]
- Delivery Days Customer7
- Antibody SpecificityThis antibody is specific for the HspX antigen from Mycobacterium tuberculosis. This antigen acts as a chaperone, as it has a significant ability to suppress the thermal denaturation of alcohol dehydrogenase. Mycobacterium tuberculosis causes the disease
- Application Supplier NoteThe binding of the scFv version of this antibody to the antigen was characterised by ELISA. Furthermore, surface plasmon resonance was used to determine the binding kinetics of this antibody on 16 kDa protein of M. tuberculosis (Sixholo et al, 2011; pmid:21349739).
- ApplicationsELISA, Other Application
- Applications SupplierELISA; SPR
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDB4m3
- Gene ID887579
- Target namehspX
- Target descriptionalpha-crystallin
- Target synonymsacr; alpha-crystallin; Rv2031c
- HostMouse
- IsotypeIgG1
- Protein IDP9WMK1
- Protein NameAlpha-crystallin
- Scientific DescriptionThis full-length, chimeric mouse antibody was made using the variable domain sequences of the original Chicken scFv format, for improved compatibility with existing reagents, assays and techniques.
- ReactivityBacteria
- Reactivity SupplierMycobacterium tuberculosis
- Reactivity Supplier NoteThis antibody was generated by first panning the Nkuku library [26] against 20 mug/ml of the M. tuberculosis 16 kDa antigen. Second a sublibrary was created using error-prone PCR. Finally the mutant library was panned against 16 kDa M. tuberculosis antigen.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203