Anti-Alpha-dystroglycan Antibody

HUABIO

Anti-Alpha-dystroglycan Antibody

7

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P,IF-Cell,FC

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

DAG1

dystroglycan 1

156DAG, A3a, AGRNR, DAG, LGMDR16, MDDGA9, MDDGC7, MDDGC9, dystroglycan 1, dystroglycan 1 (dystrophin-associated glycoprotein 1)

Rabbit

IgG

Dystroglycan 1

Dystroglycan (DG) is a cell surface receptor for several extracellular matrix molecules including laminins, Agrin and Perlecan. Dystroglycan function is required for the formation of basement membranes in early development and the organization of Laminin on the cell surface. alpha-dystroglycan is a membrane- associated, extracellular glycoprotein that is anchored to the cell-membrane by binding to the transmembrane glycoprotein alpha-dystroglycan to form an alpha/beta-dystroglycan-complex. Additionally, dystroglycan is part of a multimolecular complex, where it associates with dystrophin, at the sarcolemma, to form the dystrophin-associated protein complex, or with utrophin, at the neuromuscular junction, to form the utrophin-associated protein complex. Dystroglycan is also thought to participate in the clustering of nicotinic acetylcholine receptors at the neuromuscular junction.

Human, Mouse, Rat

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161