Anti-alpha-V beta 5 integrin [EM09902]

Absolute Antibody

Anti-alpha-V beta 5 integrin [EM09902]

9

This antibody is specific for the extracellular domain of human recombinant transmembrane-truncated (DTM) alphavbeta5 integrin, a dimeric cell surface protein that mediates cell attachment. alphavbeta5 integrin is also involved in tumour growth and angiog

This antibody has been used to specifically bind alphavbeta5 in Western blots and in flow cytometry (Goodman et al, 2012), revealing that cell lines HT29 and A549 strongly express alphavbeta5, with lower levels of expression by the M21 and M24 lines. This antibody also specifically stains alphavbeta5 in FFPE (formalin fixed paraffin embedded)/TMA material (Goodman et al, 2012; Hebeta et al., 2014; Roth et l, 2013), while murine antibodies are typically unable to detect FFPE-embedded integrins.

Flow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

EM09902

Rabbit

IgG

Human

-20°C,2°C to 8°C

12352203