Anti-AMSH Antibody [JE63-41]
HA720085
ApplicationsWestern Blot
Product group Antibodies
TargetSTAMBP
Overview
- SupplierHUABIO
- Product NameAnti-AMSH Antibody [JE63-41]
- Delivery Days Customer2
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDJE63-41
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID10617
- Target nameSTAMBP
- Target descriptionSTAM binding protein
- Target synonymsAMSH, MICCAP, STAM-binding protein, associated molecule with the SH3 domain of STAM, endosome-associated ubiquitin isopeptidase, testicular secretory protein Li 54
- HostRabbit
- IsotypeIgG
- Protein IDO95630
- Protein NameSTAM-binding protein
- Scientific DescriptionZinc metalloprotease that specifically cleaves Lys-63-linked polyubiquitin chains. Does not cleave Lys-48-linked polyubiquitin chains (By similarity). Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization (By similarity). Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161