Anti-ARF6 Antibody [JF101-2]

HUABIO

Anti-ARF6 Antibody [JF101-2]

7

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IF-Tissue,IHC-P

Research Use Only

Monoclonal

JF101-2

1 mg/ml

Unconjugated

Arf6

ARF GTPase 6

ADP-ribosylation factor 6

Rabbit

IgG

ADP-ribosylation factor 6

ADP-ribosylation factor 6 (ARF6) is a member of the ADP ribosylation factor family of GTP-binding proteins. ARF6 has a variety of cellular functions that are frequently involved in trafficking of biological membranes and transmembrane protein cargo. ARF6 has specifically been implicated in endocytosis of plasma membrane proteins and also, to a lesser extent, plasma membrane protein recycling. This gene encodes a member of the human ARF gene family, which is part of the Ras superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. ARF6 can interact with betaarrestin upon receptor activation.

Human

Human

Mouse,Rat

-20°C,2°C to 8°C

41116161