Anti-ARPC2 Antibody [JE58-79]

HUABIO

Anti-ARPC2 Antibody [JE58-79]

2

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

JE58-79

1 mg/ml

Unconjugated

ARPC2

actin related protein 2/3 complex subunit 2

ARC34, PNAS-139, PRO2446, p34-Arc, actin-related protein 2/3 complex subunit 2, ARP2/3 protein complex subunit 34, actin related protein 2/3 complex, subunit 2, 34kDa, arp2/3 complex 34 kDa subunit, testis tissue sperm-binding protein Li 53e

Rabbit

IgG

Actin-related protein 2/3 complex subunit 2

Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the mother actin filament. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs). Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined.

-20°C,2°C to 8°C

41116161