Anti asc-type Amino Acid Transporter 1 / Asc-1 pAb

Cosmo Bio USA

Anti asc-type Amino Acid Transporter 1 / Asc-1 pAb

16

Research Use Only

Mammalian amino acid transport system is consisted of large variety of transporters, with the reflection of amino acid molecule variety, and is classfied into various transport systems by the transportative substrate selectivity and the Na+ dependence with the reflection of amino acid molecule variety. asc-type amino acid transporter 1(Asc-1) is a member of the family of amino acid transporters associated with type II membrane glycoproteins , which requires an additional single membrane spanning protein, 4F2 heavy chain (4F2hc: CD98), for its functional expression. Asc-1 mediates the transport of neutral amino acid, in particular, small neutral amino acids such as Gly, L-ala, L-Ser, L-Thr and L-Cys as substrate in Na+ -independent manner. This has been proved to be useful for the immunohistochemistry.

12352203