Anti-ASC1 Antibody [PSH0-26]

HUABIO

Anti-ASC1 Antibody [PSH0-26]

2

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

PSH0-26

1 mg/ml

Unconjugated

TRIP4

thyroid hormone receptor interactor 4

ASC-1, ASC1, HsT17391, MDCDC, SMABF1, ZC2HC5, activating signal cointegrator 1, TR-interacting protein 4, TRIP-4, thyroid receptor-interacting protein 4, zinc finger, C2HC5-type

Rabbit

IgG

Activating signal cointegrator 1

This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in this gene are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1).

-20°C,2°C to 8°C

41116161