Bio-Connect

Anti-B7-H3 [MJ18]

Ab00884-2.0
Absolute Antibody
ApplicationsFlow Cytometry, Neutralisation/Blocking
Product group Antibodies
TargetCd276
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-B7-H3 [MJ18]
  • Delivery Days Customer
    7
  • Application Supplier Note
    This antibody has been used to detect murine B7-H3 by flow cytometry. It blocks B7-H3 signalling and can supress priming of Th2-responses and thereby the development of asthmatic responses in an ovalbumin-induced asthma model in BALB/c mice.
  • Applications
    Flow Cytometry, Neutralisation/Blocking
  • Applications Supplier
    FC; Block
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    MJ18
  • Gene ID102657
  • Target name
    Cd276
  • Target description
    CD276 antigen
  • Target synonyms
    6030411F23Rik; AU016588; B7 homolog 3; B7h3; B7-H3; B7RP; B7RP-2; CD276 antigen; costimulatory molecule
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDQ8VE98
  • Protein Name
    CD276 antigen
  • Scientific Description
    This chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.
  • Reactivity Supplier
    Mouse
  • Reactivity Supplier Note
    This antibody was generated by immunizing Sprague Dawley rats with B7-H3-Ig, consisting of the extracellular domain (aa1–242 of mouse B7-H3) linked to the Fc portion of mouse IgG2a, emulsified in CFA (Difco). The antibody was selected by its reactivity to mouse B7-H3-transfected cells, but not to parental cells by flow cytometry.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203

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