Anti-B7-H3 [MJ18]
Ab00884-2.0
ApplicationsFlow Cytometry, Neutralisation/Blocking
Product group Antibodies
TargetCd276
Overview
- SupplierAbsolute Antibody
- Product NameAnti-B7-H3 [MJ18]
- Delivery Days Customer7
- Application Supplier NoteThis antibody has been used to detect murine B7-H3 by flow cytometry. It blocks B7-H3 signalling and can supress priming of Th2-responses and thereby the development of asthmatic responses in an ovalbumin-induced asthma model in BALB/c mice.
- ApplicationsFlow Cytometry, Neutralisation/Blocking
- Applications SupplierFC; Block
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDMJ18
- Gene ID102657
- Target nameCd276
- Target descriptionCD276 antigen
- Target synonyms6030411F23Rik, B7-H3, B7RP-2, B7h3, CD276 antigen, B7 homolog 3, costimulatory molecule
- HostMouse
- IsotypeIgG2a
- Protein IDQ8VE98
- Protein NameCD276 antigen
- Scientific DescriptionThis chimeric mouse antibody was made using the variable domain sequences of the original Rat IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Reactivity SupplierMouse
- Reactivity Supplier NoteThis antibody was generated by immunizing Sprague Dawley rats with B7-H3-Ig, consisting of the extracellular domain (aa1–242 of mouse B7-H3) linked to the Fc portion of mouse IgG2a, emulsified in CFA (Difco). The antibody was selected by its reactivity to mouse B7-H3-transfected cells, but not to parental cells by flow cytometry.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203
![FACS analysis of mouse peritoneal macrophages using GTX42149 CD276 antibody [MJ18].](https://www.genetex.com/upload/website/prouct_img/normal/GTX42149/GTX42149_1424_FACS_w_23051500_517.webp)