More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/Anti-BAX Rabbit mAb

Anti-BAX Rabbit mAb

PTM-5300
PTM BIO
ApplicationsImmunoHistoChemistry Paraffin
Product group Antibodies
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    PTM BIO
  • Product Name
    Anti-BAX Rabbit mAb
  • Delivery Days Customer
    5
  • Applications
    ImmunoHistoChemistry Paraffin
  • Applications Supplier
    IHC-P
  • Category Supplier
    Antibody
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    JRMR-261
  • Conjugate
    Unconjugated
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ07812
  • Protein Name
    Apoptosis regulator BAX
  • Scientific Description
    Plays a role in the mitochondrial apoptotic process. Under normal conditions, BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL, which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM). Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
  • Shelf life instruction
    Stable for 12 months from date of receipt/reconstitution.
  • Reactivity Supplier
    Human, Mouse
  • Reactivity Supplier Note
    Protein A purified
  • Storage Instruction
    Store at -20°C. Avoid freeze/thaw cycles.
  • UNSPSC
    12352203

References

  • Meigui Zhang, et al. '(2E)-1-(2,4,6-Trimethoxyphenyl)-3-(4-chlorophenyl)prop-2-en-1-one, a Chalcone Derivative, Promotes Apoptosis by Suppressing RAS-ERK and AKT/FOXO3a Pathways in Hepatocellular Carcinoma Cells' CHEMISTRY & BIODIVERSITY (2023)
    Read more