Anti-Bcl-2 Antibody [9F1]
EM1701-82
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetBCL2
Overview
- SupplierHUABIO
- Product NameAnti-Bcl-2 Antibody [9F1]
- Delivery Days Customer7
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- Applications SupplierWB,IHC-P
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID9F1
- Concentration2 mg/ml
- ConjugateUnconjugated
- Gene ID596
- Target nameBCL2
- Target descriptionBCL2 apoptosis regulator
- Target synonymsBcl-2, PPP1R50, apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, protein phosphatase 1, regulatory subunit 50
- HostMouse
- IsotypeIgG
- Protein IDP10415
- Protein NameApoptosis regulator Bcl-2
- Scientific DescriptionSuppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release.
- ReactivityHuman
- Reactivity SupplierHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC41116161