Anti-BCL2A1 Antibody [SC05-42]

HUABIO

Anti-BCL2A1 Antibody [SC05-42]

7

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P,FC

Research Use Only

Monoclonal

SC05-42

1 mg/ml

Unconjugated

BCL2A1

BCL2 related protein A1

ACC-1, ACC-2, ACC1, ACC2, BCL2L5, BFL1, GRS, HBPA1, bcl-2-related protein A1, bcl-2-like protein 5, bcl2-L-5, hematopoietic BCL2-related protein A1, hemopoietic-specific early response protein, protein BFL-1

Rabbit

IgG

Bcl-2-related protein A1

The Bcl-2 family of proteins is characterized by its ability to modulate cell death under a broad range of physiological conditions. Bcl-2 and Bcl-xL function to inhibit apoptosis while other members of the Bcl-2 family, Bax, Bad, Bak and Bcl-xS, oppose death-suppressing effects. An additional member of the family, A1 (also designated Bfl-1), dimerizes with both Bcl-2 and Bax and has been identified as a hematopoietic- specific, early inducible gene. While A1 demonstrates life promoting properties similar to those of Bcl-2, its function may be more temporally regulated during myeloid differentiation and dependent on additional growth stimuli to confer its life promoting properties. A1 is abundantly expressed in bone marrow and at low levels in other tissues. There is evidence that a correlation exists between a high expression of the A1 gene product and stomach cancer.

Human, Mouse

Human,Mouse

Rat

-20°C,2°C to 8°C

41116161