Bio-Connect

Anti-BCL6 APC

1A-867
EXBIO
ApplicationsFlow Cytometry
Product group Antibodies
ReactivityHuman, Mouse
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Overview

  • Supplier
    EXBIO
  • Product Name
    Anti-BCL6 APC
  • Delivery Days Customer
    7
  • Application Supplier Note
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 microl reagent / 100 microl of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Intracellular staining.
  • Applications
    Flow Cytometry
  • Certification
    Research Use Only
  • Clone ID
    IG191E/A8
  • Conjugate
    APC (Allophycocyanin)
  • Isotype
    IgG1
  • Scientific Description
    BCL6 is a zinc finger-containing transcription factor, which acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. On B cells, BCL6 induces proliferation, antibody class switching and affinity maturation, whereas it inhibits their differentiation into plasma cells. On T cells, BCL6 induces their differentiation into T-FH cells.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203