Anti-BCR-ABL [7c6]

Absolute Antibody

Anti-BCR-ABL [7c6]

7

This antibody is specific for the SSINEEITPRRQS epitope of BCR (residues 686-696), and as such is able to recognise full-length BCR and the p210 form of the BCR-ABL fusion protein. p210 BCR-ABL is a cytogenetic marker of chronic myelogenous leukaemia, res

It has been shown by Western blot that 7c6 binds wildtype, full-length BCR and the p210 BCR-ABL fusion protein.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry

IF; IHC; WB; IP

Research Use Only

Monoclonal

7c6

Human

IgG1

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Human

Human

Murine antibodies were produced by immunising BALB/c mice with residues 686-696 (SSINEEITPRRQS) of human BCR fused to thyroglobulin. Hybridomas were generated by fusion of immunised cells with the myeloma cell line P3X63Ag8 via established methods.

-20°C,2°C to 8°C

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