Anti-beta Tubulin Antibody [1-B11]

HUABIO

Anti-beta Tubulin Antibody [1-B11]

7

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IF-Cell,IHC-P,FC

Research Use Only

Monoclonal

1-B11

2 mg/ml

Unconjugated

Tubb5

tubulin, beta 5 class I

B130022C14Rik, M(beta)5, tubulin beta-5 chain

Mouse

IgG1

Tubulin beta chain

Tubulin in molecular biology can refer either to the tubulin protein superfamily of globular proteins, or one of the member proteins of that superfamily. alpha- and beta-tubulins polymerize into microtubules, a major component of the eukaryotic cytoskeleton. Microtubules function in many essential cellular processes, including mitosis. Tubulin-binding drugs kill cancerous cells by inhibiting microtubule dynamics, which are required for DNA segregation and therefore cell division. In eukaryotes, there are six members of the tubulin superfamily, although not all are present in all species. Both alpha and beta tubulins have a mass of around 50 kDa and are thus in a similar range compared to actin (with a mass of ~42 kDa). In contrast, tubulin polymers (microtubules) tend to be much bigger than actin filaments due to their cylindrical nature. Tubulin was long thought to be specific to eukaryotes. More recently, however, several prokaryotic proteins have been shown to be related to tubulin.

Fish, Human, Mouse, Rat

Human,Mouse,Rat,Zebrafish

-20°C,2°C to 8°C

41116161