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ProductsBack/Anti-BK beta4 K+ channel [L18A/3R]

Anti-BK beta4 K+ channel [L18A/3R]

Ab02280-10.0
Absolute Antibody
ApplicationsImmunoFluorescence, Western Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetKcnmb4
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-BK beta4 K+ channel [L18A/3R]
  • Delivery Days Customer
    7
  • Antibody Specificity
    This antibody is specific for BKBeta4. It shows no cross-reactivity against BKBeta1, BKBeta2 or BKBeta3. BKBeta4 is a regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. It modulates the calcium sensitivity and gating kinetics of
  • Application Supplier Note
    This antibody was used for immunoblotting on brain tissue from rats exposed to CVS and mouse hippocampi (Yu et al, 2018; PMID:30271963). Immunofluorescence was preformed on HEK293 cells and N2a neurons with this antibody (Chen et al, 2013; PMID:23504458). Transfected HEK293 cells were immunoblotted with this antibody (Chen et al, 2013; PMID:23504458). The hippocampi of rats were immunostained with this antibody. This assay was preformed in order to assess the integrity of mossy fiber pathway and whether MaxiK channel are expressed at mossy fiber axon and terminals (Cox et al, 2014; PMID:24486049). DRG (L4/L5) from rats was used for a western blot with this antibody (Zhang et al, 2012; PMID:22607137).
  • Applications
    ImmunoFluorescence, Western Blot
  • Applications Supplier
    WB; IF
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    L18A/3R
  • Gene ID58802
  • Target name
    Kcnmb4
  • Target description
    potassium large conductance calcium-activated channel, subfamily M, beta member 4
  • Target synonyms
    1700058G18Rik; 2900045G12Rik; BK channel subunit beta-4; BKbeta4; calcium-activated potassium channel subunit beta-4; calcium-activated potassium channel, subfamily M subunit beta-4; charybdotoxin receptor subunit beta-4; k(VCA)beta-4; large conductance calcium-dependent potassium ion channel beta 4 subunit; maxi K channel subunit beta-4; slo-beta-4; Slowpoke beta 4
  • Host
    Human
  • Isotype
    IgG1
  • Protein IDQ9JIN6
  • Protein Name
    Calcium-activated potassium channel subunit beta-4
  • Scientific Description
    This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
  • Reactivity
    Human, Mouse, Rat
  • Reactivity Supplier
    mouse, human, rat
  • Reactivity Supplier Note
    This antibody was raised by immunizing a mouse with fusion protein amino acids 45-167 (entire extracellular domain) of mouse BKBeta4.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203