Anti-Botulinum neurotoxin type A [CR1]

Absolute Antibody

Anti-Botulinum neurotoxin type A [CR1]

7

Flow Cytometry

Neutralize; FC

Research Use Only

CR1

Human

IgG2a

Clostridium

CR1 was produced by a yeast gene diversity library used to increase the affinitiy of scFv AR2 for BoNT/A2, while maintinaing high affinity binding to BoNT/A2. AR2 was generated after multiple rounds of affinity maturation of the humanized C25, which itself was created by CDR-grafting from the parental murine C25. Murine C25 was prepared by constructing a scFv phage display library from mice immunized with recombinant BoNT/A binding domain (Hc).

Store at 4⁰C for up to 3 months. Note, this antibody is provided without added preservatives, it is therefore recommed this antibody be handled under sterile conditions. For longer storage, aliquot and store at -20⁰C.

12352203