Anti-BTK [10D11]

Absolute Antibody

Anti-BTK [10D11]

9

This antibody is specific for amino acids 1-175 of human BTK. It is known to bind to a 77-kD version of BTK. BTK is a non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling.

A western blot on bkt proteins using the mouse version of this antibody has proven the specificity of this clone. The antibody recognized a 77-kD BTK. Furthermore the mouse version of this antibody allows for the immunoprecipitation of the btk protein (Bykowsky et al, 1996; pmid:8644706).

ImmunoPrecipitation, Western Blot

Research Use Only

Monoclonal

10D11

BTK

Bruton tyrosine kinase

agammaglobulinaemia tyrosine kinase; AGMX1; AT; ATK; B-cell progenitor kinase; BPK; Bruton agammaglobulinemia tyrosine kinase; Bruton's tyrosine kinase; dominant-negative kinase-deficient Brutons tyrosine kinase; IGHD3; IMD1; PSCTK1; truncated Bruton agammaglobulinemia tyrosine kinase; tyrosine-protein kinase BTK; XLA

Rabbit

IgG

Tyrosine-protein kinase BTK

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203