Anti-Butyryllysine Antibody Conjugated Agarose Beads
PTM-302
ReactivityAll Species
Product group Antibodies
Overview
- SupplierPTM BIO
- Product NameAnti-Butyryllysine Antibody Conjugated Agarose Beads
- Delivery Days Customer5
- Antibody SpecificityWith the immobilization of highly specific anti-butyryllysine antibody, the Anti-Butyryllysine Antibody Conjugated Agarose Beads selectively capture peptides/proteins bearing butyryllysine residues, but do not cross-reactwith the peptides/proteins bearing other structurally similar modified residues. This product has been well utilized to affinity purify peptides for global proteomic screening of lysine butyrylation.
- Applications SupplierIAP
- Category SupplierAntibody
- CertificationResearch Use Only
- ClonalityMix
- ConjugateAgarose
- IsotypeIgG
- Scientific DescriptionLysine butyrylation is a newly identified reversible modification controlling protein activity. With integrated proteomic approaches and biochemistry analysis, lysine butyrylation has been well demonstrated in both prokaryotes and eukaryotes in wide ranges of proteins including histones and non-histone substrates. Lysine butyrylation may play a vital role in epigenetic modulation by impacting chromatin dynamics and lasticity, DNA transcriptional regulation and tumorigenesis, etc.
- Shelf life instructionStable for 12 months from date of receipt.
- ReactivityAll Species
- Reactivity SupplierAll
- Storage InstructionStore at -20°C. Avoid freeze/thaw cycles.
- UNSPSC12352203
References
- Lu Yue, et al. 'Dynamics and functional interplay of histone lysine butyrylation, crotonylation, and acetylation in rice under starvation and submergence' GENOME BIOLOGY (2018)Read more
- Jun-Yu Xu, et al. 'Protein Acylation is a General Regulatory Mechanism in Biosynthetic Pathway of Acyl-CoA-Derived Natural Products' Cell Chemical Biology (2018)Read more
- Cluntun Ahmad A., et al. 'The rate of glycolysis quantitatively mediates specific histone acetylation sites' Cancer & Metabolism (2015)Read more
- Jun-Yu Xu, et al. 'Protein Acetylation and Butyrylation Regulate the Phenotype and Metabolic Shifts of the Endospore-forming Clostridium acetobutylicum*' MOLECULAR & CELLULAR PROTEOMICS (2018)Read more