Anti-C3a-receptor [2A1]

Absolute Antibody

Anti-C3a-receptor [2A1]

7

The original scFv antibody binds to the 2e loop of the human C3a receptor in an ELISA. Human C3a receptor is a G protein-coupled receptor stimulating chemotaxis, superoxide anion generation and granule enzyme release. This antibody was able to bind RBL-2H3 cells stably expressing the C3aR and to the human mast cell line HMC-1 in a flow cytometric assay. This antibody is not capable of blocking the interaction between C3a and C3aR (PMID: 11373092).

Flow Cytometry, ELISA

ELISA; FC

Research Use Only

C3a anaphylatoxin chemotactic receptor

This full-length chimeric rabbit antibody was made using the variable domain sequences of the original Mouse scFv format for improved compatibility with existing reagents assays and techniques.

-20°C,2°C to 8°C

12352203