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Anti-C5 [Eculizumab]

Ab00296-1.1
Absolute Antibody
ApplicationsElectron Microscopy, ELISA, Neutralisation/Blocking
Product group Antibodies
TargetC5
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-C5 [Eculizumab]
  • Delivery Days Customer
    7
  • Application Supplier Note
    This antibody inhibits activation of C5. The human Fab version (Ab00296-10.6) of this antibody was used by Jore et al. (2016, PMID: 27018802) to determine the binding site of this antibody to C5.
  • Applications
    Electron Microscopy, ELISA, Neutralisation/Blocking
  • Applications Supplier
    Block; EM; ELISA
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    Eculizumab
  • Gene ID727
  • Target name
    C5
  • Target description
    complement C5
  • Target synonyms
    anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4; C5a; C5a anaphylatoxin; C5b; C5D; complement C5; complement component 5; CPAMD4; ECLZB; prepro-C5
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP01031
  • Protein Name
    Complement C5
  • Scientific Description
    This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG2/4 format, for improved compatibility with existing reagents, assays and techniques.
  • Reactivity Supplier
    Human
  • Reactivity Supplier Note
    C5 is activated by C5 converatse into C5a, an anaphylatoxin, and C5b a component of the membrane attack complex.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203

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