Anti-C5 [Eculizumab]

Absolute Antibody

Anti-C5 [Eculizumab]

7

This antibody inhibits activation of C5. The human Fab version (Ab00296-10.6) of this antibody was used by Jore et al. (2016, PMID: 27018802) to determine the binding site of this antibody to C5.

Electron Microscopy, ELISA, Neutralisation/Blocking

Block; EM; ELISA

Research Use Only

Monoclonal

Eculizumab

C5

complement C5

C5D, C5a, C5b, CPAMD4, ECLZB, complement C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, C5a anaphylatoxin, anaphylatoxin C5a analog, complement component 5, prepro-C5

Mouse

IgG1

Complement C5

This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG2/4 format, for improved compatibility with existing reagents, assays and techniques.

Human

C5 is activated by C5 converatse into C5a, an anaphylatoxin, and C5b a component of the membrane attack complex.

-20°C,2°C to 8°C

12352203