Anti-C5aR [S5/1]

Absolute Antibody

Anti-C5aR [S5/1]

7

S5/1 antibody inhibits C5a binding to its receptor C5aR (Oppermann et al., 1993). Furthermore, this antibody has been widely applied in the detection and analysis of C5aR via various methods. For instance, it was used in a flow cytometric study on peripheral blood lymphocytes where it was shown to bind to monocytes and granulocytes (Oppermann et al., 1993). It was also utilized in the Western blot experiments comparing C5aR expression in different groups of mice (Panayiotou et al., 2017). S5/1 was also successfull in labelling C5aR in the paraffin-embedded immunohistochemical samples of umbilical arteries (Fortin et al., 2002).

Functional Assay, Flow Cytometry, ImmunoPrecipitation, Western Blot, ELISA, Neutralisation/Blocking

blocking; WB; FC; IP; ELISA; functional studies

Research Use Only

Monoclonal

S5/1

C5AR1

complement C5a receptor 1

C5A; C5a anaphylatoxin chemotactic receptor 1; C5a anaphylatoxin receptor; C5a ligand; C5AR; C5a-R; C5R1; CD88; complement component 5a receptor 1

Human

IgG1

C5a anaphylatoxin chemotactic receptor 1

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Human, Rabbit, Cow, Ferret

This antibody was raised by immunizing mice with a synthetic peptide corresponding to C5a-R; amino acids: 1-31 (N terminal).

-20°C,2°C to 8°C

12352203