Anti-CA125 [196-14]
Ab00525-1.1
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetMUC16
Overview
- SupplierAbsolute Antibody
- Product NameAnti-CA125 [196-14]
- Delivery Days Customer7
- Antibody SpecificityThe antibody binds to CA125 with a Kd of 0.83 nM reported for the original antibody.
- Application Supplier NoteThe antibody binds specifically to CA125, membrane associated glycoprotein which acts as a biomarker for ovarian cancer detection, and is also associated with endometrial, fallopian tube, lung, breast and gastrointestinal tract cancers. CA125 plays an important role in tumorigenesis by enhancing the metastasis of tumour cells, increasing immune system evasion, inducing motility and resistance to chemotherapy. The monoclonal antibody 196-14 can be used for both in vivo and in vitro applications, and potentially in the diagnosis and treatment of endometrial or ovarian cancers expressing high levels of CA125.
- ApplicationsELISA, ImmunoHistoChemistry
- Applications SupplierELISA; IHC
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID196-14
- Gene ID94025
- Target nameMUC16
- Target descriptionmucin 16, cell surface associated
- Target synonymsCA125; CA125 ovarian cancer antigen; cancer antigen 125; mucin-16; ovarian cancer-related tumor marker CA125; ovarian carcinoma antigen CA125
- HostMouse
- IsotypeIgG1
- Protein IDQ8WXI7
- Protein NameMucin-16
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier NoteHOUA-1 cells from endometrial cancer.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203