Anti-CACNG2 Antibody

HUABIO

Anti-CACNG2 Antibody

7

Flow Cytometry, ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P,IF-Cell,FC

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

CACNG2

calcium voltage-gated channel auxiliary subunit gamma 2

MRD10, voltage-dependent calcium channel gamma-2 subunit, TARP gamma-2, neuronal voltage-gated calcium channel gamma-2 subunit, stargazin, transmembrane AMPAR regulatory protein gamma-2

Rabbit

IgG

Voltage-dependent calcium channel gamma-2 subunit

Calcium channel, voltage-dependent, gamma subunit 2, also known as CACNG2 or stargazin is a protein that in humans is encoded by the CACNG2 gene. L-type calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of several gamma subunit proteins. It is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This protein is similar to the mouse stargazin protein, mutations in which having been associated with absence seizures, also known as petit-mal or spike-wave seizures. This gene is a member of the neuronal calcium channel gamma subunit gene subfamily of the PMP-22/EMP/MP20 family. Stargazin is involved in the transportation of AMPA receptors to the synaptic membrane, and the regulation of their receptor rate constants - via its extracellular domain - once it is there. As it is highly expressed throughout the cerebral cortex, it is likely to have an important role in learning within these areas, due to the importance of AMPA receptors in LTP.

Human, Mouse, Rat

Human,Mouse,Rat

-20°C,2°C to 8°C

41116161