Anti-Carbonic Anhydrase 2 / CA2 Rat mAb

PTM BIO

Anti-Carbonic Anhydrase 2 / CA2 Rat mAb

5

Western Blot

WB

Research Use Only

Monoclonal

12207

Unconjugated

Rat

IgG

Carbonic anhydrase 2

Carbonic anhydrase II is one of sixteen forms of human alfa carbonic anhydrases. The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions). The active site of most carbonic anhydrases contains a zinc ion. They are therefore classified as metalloenzymes. The enzyme maintains acid-base balance and helps transport carbon dioxide. Carbonic anhydrase helps maintain acid–base homeostasis, regulate pH, and fluid balance. Depending on its location, the role of the enzyme changes slightly. Renal carbonic anhydrase allows the reabsorption of bicarbonate ions in the proximal tubule. Loss of carbonic anhydrase activity in bones impairs the ability of osteoclasts to promote bone resorption, leading to osteopetrosis.

Stable for 12 months from date of receipt/reconstitution.

Human, Mouse

Human, Mouse

Protein G purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203