Bio-Connect

Anti-Caspase-9 Mouse mAb

PTM-5311
PTM BIO
ApplicationsWestern Blot
Product group Antibodies
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    PTM BIO
  • Product Name
    Anti-Caspase-9 Mouse mAb
  • Delivery Days Customer
    5
  • Applications
    Western Blot
  • Applications Supplier
    WB
  • Category Supplier
    Antibody
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    12124
  • Conjugate
    Unconjugated
  • Host
    Mouse
  • Isotype
    IgG
  • Protein IDP55211
  • Protein Name
    Caspase-9
  • Scientific Description
    Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).
  • Shelf life instruction
    Stable for 12 months from date of receipt/reconstitution.
  • Reactivity Supplier
    Human
  • Reactivity Supplier Note
    Protein G purified
  • Storage Instruction
    Store at -20°C. Avoid freeze/thaw cycles.
  • UNSPSC
    12352203

References

  • Zhang Ting, et al. 'G6PD maintains the VSMC synthetic phenotype and accelerates vascular neointimal hyperplasia by inhibiting the VDAC1–Bax-mediated mitochondrial apoptosis pathway' CELLULAR & MOLECULAR BIOLOGY LETTERS (2024)
    Read more