Anti-Cathepsin B Antibody [J11-A11]

HUABIO

Anti-Cathepsin B Antibody [J11-A11]

7

ImmunoFluorescence, Western Blot

WB,IF-Cell,IHC-P

Research Use Only

Monoclonal

J11-A11

2 mg/ml

Unconjugated

CTSB

cathepsin B

APPS, CPSB, KWE, RECEUP, cathepsin B, APP secretase, amyloid precursor protein secretase, cathepsin B1, cysteine protease, epididymis secretory sperm binding protein, keratolytic winter erythema (Oudtshoorn skin disease)

Mouse

IgG1

Cathepsin B

Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. In humans, it is coded by the CTSB gene. A wide array of diseases results in elevated levels of cathepsin B, which causes numerous pathological processes including cell death, inflammation, and production of toxic peptides. Focusing on neurological diseases, cathepsin B gene knockout studies in an epileptic rodent model have shown cathepsin B causes a significant amount of the apoptotic cell death that occurs as a result of inducing epilepsy. Mutations in the CTSB gene have been linked to tropical pancreatitis, a form of chronic pancreatitis

Fish, Human

Human,Zebrafish

-20°C,2°C to 8°C

41116161