Anti-Cathepsin B Rabbit mAb

PTM BIO

Anti-Cathepsin B Rabbit mAb

5

Western Blot

WB

Research Use Only

Monoclonal

JRMR-10043-56

Unconjugated

Rabbit

IgG

Cathepsin B

Cathepsin B is a member of the C1 family of peptidases. This protein is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease. Overexpression of Cathepsin B has been associated with esophageal adenocarcinoma and other tumors. Both Cathepsin B and Cathepsin L are involved in the cleavage of the spike protein from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) upon its entry to the human host cell.

Stable for 12 months from date of receipt/reconstitution.

Human

Human

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203