Anti-CBP Rabbit mAb

PTM BIO

Anti-CBP Rabbit mAb

5

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

WB, ICC/IF

Antibody

Research Use Only

Monoclonal

10707

Unconjugated

Rabbit

IgG

CREB-binding protein

CREB-binding protein (CREBBP/CBP), encoded by the human CREBBP gene, is a transcriptional co-activator. CREBBP functions through interactions with transcription factors, mediated by one or more domains: the nuclear receptor interaction domain (RID), the KIX domain (CREB and MYB interaction domain), the cysteine/histidine regions (TAZ1/CH1 and TAZ2/CH3), and the interferon response binding domain. The KIX, TAZ1, and TAZ2 domains of CREBBP bind tightly to the 9aaTADs, the nine amino acid transactivation domains within the tumor suppressor protein p53, thereby influencing its transcriptional activity.

Stable for 12 months from date of receipt/reconstitution.

Human

Protein A purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203