Anti-CCR2 [4.9]

Absolute Antibody

Anti-CCR2 [4.9]

9

The binding specificity of this antibody to full length CCR2, and 1St and 2nd loop of CCR2 was determined using ELISA. The binding reactivity of this antibody to the surface bound CCR2 receptors was confirmed with flow cytometry. This antibody can positively inhibit chemotaxis of THP-1 monocytes. The therapeutic effects of this antibody were studied in in vivo mouse models of inflammation, multiple sclerosis and neuropathic pain (US8710191).

Flow Cytometry, ELISA, Other Application

Research Use Only

Monoclonal

4.9

CCR2

C-C motif chemokine receptor 2

CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R, PCLUD, C-C chemokine receptor type 2, MCP-1 receptor, chemokine (C-C motif) receptor 2, monocyte chemoattractant protein 1 receptor, monocyte chemotactic protein 1 receptor

Rabbit

IgG

C-C chemokine receptor type 2

This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format for improved compatibility with existing reagents assays and techniques.

Human

-20°C,2°C to 8°C

12352203