anti-CD11a / LFA1 alpha antibody [I21/7]

Arigo Biolaboratories

anti-CD11a / LFA1 alpha antibody [I21/7]

23

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking

Research Use Only

Monoclonal

I21/7

0.5 mg/ml

Unconjugated

Itgal

integrin alpha L

(p180), Cd11a, LFA-1, LFA-1A, Ly-15, Ly-21, integrin alpha-L, CD11 antigen-like family member A, alpha L integrin, leukocyte adhesion glycoprotein LFA-1 alpha chain, leukocyte function-associated molecule 1 alpha chain, lymphocyte antigen 15, lymphocyte function associated antigen 1, alpha polypeptide

Rat

IgG2a

ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Mouse

-20°C

12352203