Anti-CD11b [ICRF44]

Absolute Antibody

Anti-CD11b [ICRF44]

9

This antibody recognizes CD11b (Integrin alpha-M) which is an adhesion molecule. CD11b associated with integrin beta2 (CD18) is expressed on the surface of monocytes, granulocytes, activated lymphocytes and a subset of NK cells. CD11b is a receptor for in

This antibody is recommended for the detection and analysis of CD11b (Integrin alpha-M) and CD11b-plus cells in lineage identification. The original mouse IgG1 format of this clone has been widely used in various flow cytometry experiments. For instance, ICRF44 was applied in an FC analysis of cells during MDSCs generation (Eriksson et al., 2019; pmid: 30617223). Another group screened mouce splenocytes with this antibody during tumor studies (Horn et al., 2017; pmid: 28938530). Jardine et al. (2019) utilized this clone to phenotype blood DC cells (pmid: 31040289). Similarly, this antibody was used as a part of a wider panel to phenotype MUTZ-3 and MUTZ-LCs cells (Bock et al., 2016; pmid: 26794428).

Flow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry

Research Use Only

Monoclonal

ICRF44

ITGAM

integrin subunit alpha M

antigen CD11b (p170); CD11 antigen-like family member B; CD11B; cell surface glycoprotein MAC-1 subunit alpha; complement component 3 receptor 3 subunit; CR-3 alpha chain; CR3A; integrin alpha-M; integrin, alpha M (complement component 3 receptor 3 subunit); leukocyte adhesion receptor MO1; MAC-1; MAC1A; macrophage antigen alpha polypeptide; macrophage-1 antigen alpha subunit; MO1A; neutrophil adherence receptor alpha-M subunit; SLEB6

Rabbit

IgG

Integrin alpha-M

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human, Monkey, Porcine, Primate

-20°C,2°C to 8°C

12352203