Anti-CD11b [VHHCD11b], Mouse IgG1-Fc Fusion,

Absolute Antibody

Anti-CD11b [VHHCD11b], Mouse IgG1-Fc Fusion,

9

The antibody is specific for CD11b.

The original format of the antibody specifically bound to CD11b+ cells in lymph nodes and spleen by two-photon microscopy and flow cytometry analysis. 18F-labelled antibody was used for noninvasive imaging of CD11b+ cells, both in normal and in tumor-bearing mice (Rashidian et al., 2015; PMID: 25902531). The antibody was conjugated to an H-2Db -restricted immunodominant E7 epitope (an HPV tumor antigen peptide) for treatment of HPV induced cancer (Woodham et al., 2018; PMID: 29792298).

Flow Cytometry, ImmunoFluorescence

Research Use Only

Monoclonal

VHHCD11b

Mouse

IgG1

Integrin alpha-M

This is a chimeric antibody, developed from the original camelid VHH antibody, specifically engineered for enhanced compatibility with existing reagents, assays, and techniques.

Mouse

-20°C,2°C to 8°C

12352203