Anti-CD130 / GP130 Antibody [B11-B9-A8]

HUABIO

Anti-CD130 / GP130 Antibody [B11-B9-A8]

7

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P,IF-Cell

Research Use Only

Monoclonal

B11-B9-A8

2 mg/ml

Unconjugated

IL6ST

interleukin 6 cytokine family signal transducer

CD130, CDW130, GP130, HIES4, HIES4A, HIES4B, IL-6RB, IMD94, STWS2, sGP130, interleukin-6 receptor subunit beta, CD130 antigen, IL-6 receptor subunit beta, IL-6R subunit beta, gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form, gp130, oncostatin M receptor, interleukin receptor beta chain, interleukin-6 signal transducer, membrane glycoprotein 130, membrane glycoprotein gp130, oncostatin-M receptor subunit alpha

Mouse

IgG2b

Interleukin-6 receptor subunit beta

Glycoprotein 130 (also known as gp130, IL6ST, IL6R-beta or CD130) is a transmembrane protein which is the founding member of the class of all cytokine receptors. It forms one subunit of the type I cytokine receptor within the IL-6 receptor family. It is often referred to as the common gp130 subunit, and is important for signal transduction following cytokine engagement. As with other type I cytokine receptors, gp130 possesses a WSXWS amino acid motif that ensures correct protein folding and ligand binding. It interacts with Janus kinases to elicit an intracellular signal following receptor interaction with its ligand. Structurally, gp130 is composed of five fibronectin type-III domains and one immunoglobulin-like C2-type (immunoglobulin-like) domain in its extracellular portion.

Human

Human

-20°C,2°C to 8°C

41116161