anti-CD134 / OX40 antibody [7D6]
ARG23160
ApplicationsFlow Cytometry, Western Blot
Product group Antibodies
ReactivityFeline
TargetTNFRSF4
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-CD134 / OX40 antibody [7D6]
- Delivery Days Customer23
- ApplicationsFlow Cytometry, Western Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID7D6
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID493665
- Target nameTNFRSF4
- Target descriptionTNF receptor superfamily member 4
- Target synonymsCD134; OX40; tumor necrosis factor receptor superfamily member 4; tumor necrosis factor receptor superfamily, member 4
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]
- ReactivityFeline
- Storage Instruction-20°C
- UNSPSC12352203