Bio-Connect

Anti-CD147 [PPAT-082-03]

Research Use Only
Ab03042-1.1
Absolute Antibody
ApplicationsFlow Cytometry, ELISA
Product group Antibodies
ReactivityHuman, Monkey
TargetBSG
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-CD147 [PPAT-082-03]
  • Delivery Days Customer
    7
  • Antibody Specificity
    This antibody binds human and cynomolgus monkey CD147. CD147 is a type I membrane glycoprotein and is classified into the immunoglobulin-like superfamily, and is expressed in many types of cancer. It is suggested that CD147 is also associated with cancer
  • Application Supplier Note
    The binding specificity of this antibody for human and cynomolgus monkey was determined using ELISA. This antibody was shown to interact with CD147 expressed on Raji cells and HSC-F cells in a flow cytometric analysis. This antibody was also reported to show anti-tumor effects in tumor-bearing mouse model of K562 cells, which is a chronic leukemia cell line and in tumor-bearing mouse model of SW480 cells, a colon cancer cell line. This antibody also showed CDC and ADCC activity against CD147 bearing cancerous cells (WO2017061602).
  • Applications
    Flow Cytometry, ELISA
  • Applications Supplier
    ELISA; FC
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    PPAT-082-03
  • Gene ID682
  • Target name
    BSG
  • Target description
    basigin (Ok blood group)
  • Target synonyms
    5F7; basigin; CD147; collagenase stimulatory factor; EMMPRIN; EMPRIN; extracellular matrix metalloproteinase inducer; HAb18G; hepatoma-associated antigen; leukocyte activation antigen M6; OK; OK blood group antigen; SLC7A11; TCSF; tumor cell-derived collagenase stimulatory factor
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP35613
  • Protein Name
    Basigin
  • Reactivity
    Human, Monkey
  • Reactivity Supplier
    Human, cynomolgus monkey
  • Reactivity Supplier Note
    The original antibody was generated by immunizing BALB/c mice with extracellular domain of CD147-His and 50 mug / head, 100 ng / head of pertussis toxin in Freund's complete adjuvant.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203