Anti-CD151 [11G5a]

Absolute Antibody

Anti-CD151 [11G5a]

9

This antibody binds to the CD151-integrin alpha3beta1 binding site of the CD151 extracellular domain.

The antibody has been used in flow cytometry experiments and to assess the interaction of CD151 with integrins (Yauch 1998). CD151 can also regulate cell migration independent of integrins in cancer for tumour cell migration, and mAb 11G5a has been used for histologic detection of CD151 free in prostate cancer, which correlates with poor patient outcome (TD Palmer 2014).

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Monoclonal

11G5a

CD151

CD151 molecule (Raph blood group)

CD151 antigen; CD151 antigen (Raph blood group); GP27; hemidesmosomal tetraspanin CD151; membrane glycoprotein SFA-1; MER2; PETA-3; platelet surface glycoprotein gp27; platelet-endothelial cell tetraspan antigen 3; platelet-endothelial tetraspan antigen 3; RAPH; SFA1; tetraspanin-24; TSPAN24; tspan-24

Human

IgG1

CD151 antigen

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

12352203