anti-CD18 (human), mAb (IB4) (Fab)

Ancell Corporation

anti-CD18 (human), mAb (IB4) (Fab)

10

Flow Cytometry, Neutralisation/Blocking

Research Use Only

Monoclonal

IB4

1 mg/ml

Mouse

IgG2a

Human CD18 (beta2 integrin) forms a heterodimer with either alphaL, alphaM, or alphaX integrins (CD11a, b or c). CD11/CD18 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. Antibody IB4 recognizes the beta 2 integrin subunit (CD18) adhesion molecule of about 95 kd. Antibody IB4 blocks binding of ICAM-1 and ICAM-3 to LFA-1. - Monoclonal Antibody. Applications: FACS, FUNC (Blocking). Clone: IB4. Isotype: Mouse IgG2a. 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl. Preservative free. Human CD18 (beta2 integrin) forms a heterodimer with either alphaL, alphaM, or alphaX integrins (CD11a, b or c). CD11/CD18 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. Antibody IB4 recognizes the beta 2 integrin subunit (CD18) adhesion molecule of about 95 kd. Antibody IB4 blocks binding of ICAM-1 and ICAM-3 to LFA-1.

Human, Primate, Rabbit

2°C to 8°C

12352203