Anti-CD18 [YFC51.1]

Absolute Antibody

Anti-CD18 [YFC51.1]

7

The original rat IgG2b version of this antibody was successful in blocking CD18. The human IgG1 version of this antibody was able to block CD18 but unable to bind human Clq and did not mediate antibody-dependent cellular cytotoxicity (PMID: 7688398). This antibody was used as one of the antibodies to study the effect of anti-LFA-1 panel of abs on T cell adhesion to ICAM-1 and ICAM-3 using ELISA (PMID: 7518468).

ELISA, Neutralisation/Blocking

Block; ELISA

Research Use Only

Monoclonal

YFC51.1

ITGB2

integrin subunit beta 2

CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7, integrin beta-2, cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor), complement component 3 receptor 3 and 4 subunit, complement receptor C3 beta-subunit, integrin beta chain, beta 2, integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), leukocyte cell adhesion molecule CD18, leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C

Rabbit

IgG

Integrin beta-2

This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2b format for improved compatibility with existing reagents assays and techniques.

-20°C,2°C to 8°C

41116161