Anti-CD19 [26D3]

Absolute Antibody

Anti-CD19 [26D3]

7

The antibody is specific for CD19. Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens.

The antibody detected the recombinant CD19 by western blot analysis. The antibody was used to stain and analyze prostate tissue, B-cell lymphoma samples and tonsil B lymphocytes by immunohistochemistry. Further, immunohistochemistry staining from 26D3 antibody and the commercial antibody, LE-CD19, were compared. Results showed that the specificity of the 26D3 antibody in tumor tissue was equivalent to the commercial antibody, while sensitive and affinity were higher than the commercial antibody (CN103880960).

Western Blot, ELISA, ImmunoHistoChemistry

ELISA; WB; IHC

Research Use Only

Monoclonal

26D3

CD19

CD19 molecule

B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; CVID3; differentiation antigen CD19; T-cell surface antigen Leu-12

Rabbit

IgG

B-lymphocyte antigen CD19

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.

Human

Human

The original antibody was generated by immunizing mice with CD19.

-20°C,2°C to 8°C

12352203