Anti-CD19 [6D5]

Absolute Antibody

Anti-CD19 [6D5]

7

This antibody recognises mouse CD19, which is a transmembrane glycoprotein that regulates B lymphocyte development, activation, and differentiation. This clone 6D5 recognizes the same epitope as the published clone 1D3.

6D5 antibody has been extensively used to identify B cells in various experimental arrangements. It can be efficiently utilised in the localisation of B cells in various tissues. For instance, one group stained murine spleen tissue cryosections to visualise lymphomas in azathioprine-treated mice (Chalastanis et al., 2010). This antibody has also been widely used in flow cytometry. One group utilised in the flow cytometric identification of B cells in a study investigating the relation of microglia depletion and MPTP neurotoxicity (Yang et al., 2018).

Flow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry

FC; IHC; IP; WB

Research Use Only

Monoclonal

6D5

CD19

CD19 molecule

B4; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; CVID3; differentiation antigen CD19; T-cell surface antigen Leu-12

Mouse

IgG2a

B-lymphocyte antigen CD19

This is a bispecific, knob-into-hole heterodimerized antibody, with one arm directed against mouse CD19 (Fab) and one arm directed against mouse CD3e (scFv).

Mouse

Mouse

This antibody was raised by immunising rats with mouse CD19-expressing K562 human erythroleukemia cells.

-20°C,2°C to 8°C

12352203