Anti-CD19 Mouse mAb

PTM BIO

Anti-CD19 Mouse mAb

5

Flow Cytometry

FC

Research Use Only

Monoclonal

11864

Unconjugated

Mouse

IgG

B-lymphocyte antigen CD19

B-lymphocyte antigen CD19, also known as CD19 molecule (Cluster of Differentiation 19), B-Lymphocyte Surface Antigen B4, T-Cell Surface Antigen Leu-12 and CVID3 is a transmembrane protein that in humans is encoded by the gene CD19.In humans, CD19 is expressed in all B lineage cells. Contrary to some early doubts, human plasma cells do express CD19, as confirmed by others. CD19 plays two major roles in human B cells. It acts as an adaptor protein to recruit cytoplasmic signaling proteins to the membrane and it works within the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways. Due to its presence on all B cells, it is a biomarker for B lymphocyte development, lymphoma diagnosis and can be utilized as a target for leukemia immunotherapies.

Stable for 12 months from date of receipt/reconstitution.

Human

Human

Protein G purified

Store at -20°C. Avoid freeze/thaw cycles.

12352203