Anti-CD19/CD20 CAR-T Cells
82481
CategoryCells Cell Lines
Product group Cell Culture
Overview
- SupplierBPS Bioscience
- Product NameAnti-CD19/CD20 CAR-T Cells
- Delivery Days Customer23
- ApplicationsOther Application
- CertificationResearch Use Only
- Gene ID930
- Target nameCD19
- Target descriptionCD19 molecule
- Target synonymsB4, CVID3, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, T-cell surface antigen Leu-12, differentiation antigen CD19
- Protein IDP11836
- Protein NameB-lymphocyte antigen CD20
- Scientific DescriptionAnti-CD19/CD20 CAR-T Cells are produced by high-titer lentiviral transduction of human primary CD4+ and CD8+ T cells using Anti-CD19/CD20 CAR Lentivirus. These ready-to-use CAR (chimeric antigen receptor)-T cells express an anti-CD19/CD20 CAR consisting of the ScFv portions of both anti-CD20 (Clone OMB-157) and anti-CD19 (clone FMC63) linked to a second generation CAR containing IgG4 hinge and CD28 transmembrane domains, 4-1BB and CD3aeta signaling domains (Figure 1).These CAR-T cells have been validated using flow cytometry (to determine CAR expression) and co-culture cytotoxicity assays. Figure 1. Construct diagram showing components of the Anti-CD19/CD20 CAR expressed in Anti-CD19/CD20 CAR-T Cells.
- Storage InstructionLiquid Nitrogen
- UNSPSC41116106
- SpeciesHuman