Anti-CD20 [2H7]

Absolute Antibody

Anti-CD20 [2H7]

7

This antibody is specific for CD20, which is expressed by normal and malignant B cells.

This antibody has been used in flow cytometry and quantitative immunofluorescence analysis of human peripheral blood mononuclear leukocytes (Yanase et al, 1986).It has also been used to precipitate CD20 from lysates of the Raji human B cell line (Deans et al, 1995). This antibody has been exploited as part of a an avidin-biotin immunoadsorption system to eliminate Daudi lymphoblasts from human bone marrow (Berenson et al, 1986). A mouse-human chimeric version of this antibody effectively mediates antibody-dependent cellular cytotoxicity with human effector cells and complement-dependent cytotoxicity with human complement (Liu et al, 1987).

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation

FC; IF; IP

Research Use Only

Monoclonal

2H7

MS4A1

membrane spanning 4-domains A1

B1; B-lymphocyte antigen CD20; B-lymphocyte cell-surface antigen B1; Bp35; CD20; CD20 antigen; CD20 receptor; CVID5; FMC7; LEU-16; leukocyte surface antigen Leu-16; membrane-spanning 4-domains, subfamily A, member 1; S7

Mouse

IgG2b

B-lymphocyte antigen CD20

Human, Monkey, Primate

Human, chimpanzee, gibbon, baboon, langur, owl monkey, marmoset

This antibody was raised by hyperimmunising a C57BL/6 mouse with the Ia- B cell line 6.16 cl. 3.

-20°C,2°C to 8°C

12352203